The Application of Nitrogen-filled sealing machines in Biotechnology.
In the field of biotechnology, nitrogen gas sealing machines play a crucial role in creating an oxygen-free environment, which is essential for the preservation of biological samples, packaging of biological preparations and vaccines, protection during cell culture and fermentation processes, and support in laboratory and research settings. The specific applications are as follows:
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1. Preservation of Biological Samples
Cell, Tissue, and Blood Preservation: Biological samples (such as cells, tissues, and blood) have strict requirements for their preservation environment, with oxygen being a significant factor causing oxidation and deterioration. Nitrogen gas sealing machines can provide a stable, oxygen-free preservation environment, effectively extending the survival time and activity of biological samples. For instance, during cell culture, nitrogen-filled packaging can prevent cells from dying due to oxidation during storage and transportation, ensuring their integrity and functionality.
Microbial Preservation: For certain oxygen-sensitive microorganisms (such as anaerobic bacteria), nitrogen-filled packaging can provide a suitable survival environment, preventing their death or mutation during storage.
2. Packaging of Biological Preparations and Vaccines
Protection of Biological Preparations: Biological preparations (such as protein drugs and enzyme preparations) are highly sensitive to temperature, humidity, and oxygen content. Nitrogen gas sealing machines can ensure the safety and effectiveness of these products during storage and transportation, preventing a decrease in activity or failure due to environmental factors. For example, certain protein drugs are prone to oxidation and degradation in the presence of oxygen, and nitrogen-filled packaging can significantly extend their shelf life.
Vaccine Packaging: Vaccines have extremely high requirements for storage conditions, and even minor environmental changes can affect their immune efficacy. Nitrogen gas sealing machines can provide a stable, oxygen-free packaging environment for vaccines, ensuring their safety and effectiveness during storage and transportation.
3. Protection during Cell Culture and Fermentation Processes
Cell Culture: During cell culture, oxygen is an important factor in cell metabolism, but excessive oxygen can also cause oxidative damage to cells. Nitrogen gas sealing machines can regulate the oxygen concentration during cell culture, providing an appropriate survival environment for cells and promoting their growth and reproduction.
Fermentation Process Protection: During fermentation, the growth and metabolism of microorganisms require specific environmental conditions. Nitrogen gas sealing machines can control the oxygen concentration in the fermentation tank, regulating the metabolic pathways of microorganisms and increasing the yield and quality of fermentation products. For example, in alcohol fermentation, nitrogen-filled packaging can prevent oxygen from entering the fermentation tank, inhibit the growth of contaminants, and increase alcohol production.
4. Laboratory and Research Support
Preservation of Laboratory Samples: Many laboratory samples (such as chemical reagents and biological samples) need to be stored for long periods and are sensitive to oxygen. Nitrogen gas sealing machines can provide an oxygen-free environment, ensuring the integrity and stability of samples and supporting the smooth progress of related research work.
Packaging of Laboratory Equipment: Some laboratory equipment (such as test tubes and culture dishes) need to be kept sterile and dry. Nitrogen gas sealing machines can meet this requirement, preventing contamination or damage to the equipment during storage.


